The Rabbit anti-human DNA-binding protein inhibitor ID-2 polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ID2. This antibody recognizes Human antigen. The Rabbit anti-human DNA-binding protein inhibitor ID-2 polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
D (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.
This protein belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene